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Thursday, October 21, 2021, 9:12 AM

Doxepin: An Easy Treatment For Anxiety And Depression

What is Doxepin? How does it work?
Doxepin is strongly recommended for the treatment of:
    - Psychoneurotic patients suffering from anxiety and depression
    - Anxiety and depression are linked with alcoholism.
    - Anxiety and depression are linked with organic diseases.
    - Psychotic depressive disorders are linked with anxiety, manic-depressive disorders, and involution depression.
    - Symptoms of psychoneurosis including depression, anxiety, somatic symptoms, tensions, guilt, sleep disturbances, worry, and apprehension
Doxepin has been shown by clinical experience as being well-tolerated and safe. Owing to the lack of clinical experience, doxepin capsules are generally not recommended by children under the age of 12.
Doxepin: Strengths and forms
    1. Capsule (generic)
    - 150 mg
    - 100 mg
    - 75 mg
    - 50 mg
    - 25 mg
    - 10 mg
    1. Tablet (silenor)
    - 6 mg
    - 3 mg
    1. Oral concentrate (generic)
    - 10 mg/mL


What are the side effects known to be associated with the use of doxepin?
Side effects associated with the use of doxepin include:
    - Anxiety
    - Agranulocytosis
    - Agitation
    - Blurred vision
    - Constipation
    - Confusion
    - Drowsiness
    - Dry mouth
    - Dizziness
    - ECG changes
    - Extrapyramidal symptoms
    - Eosinophilia
    - Fatigue
    - Fast heart rate
    - Headache
    - Insomnia
    - Increased LFTs
    - Lethargy
    - Low WBC count
    - Low blood platelet count
    - Numbness and tingling
    - Nausea
    - Rash
    - Ringing in ears
    - Sweating
    - Sexual dysfunction
    - Seizures
    - SINDH
    - Vomiting
    - Weakness


What are the warnings for doxepin to look for?
    - Through short-term studies, it has been seen that antidepressants tend to increase the risk of people thinking about suicide. It also affects adolescents, children, and young adults (those under the age of 24 years) who take antidepressants for psychiatric illnesses and other major depressive disorders.
    - Such an increase was not seen in patients over the age of 24 years. A slight decline in the number of adults over 65 years was noticed about suicidal thinking.
    - Patients should always be closely monitored for any changes in behaviour, suicidal tendencies, and clinical worsening. This should be done during the initial period of 1-2 months of dosage adjustments and therapies.
    - In young adults and children, associated risks must be weighed against the advantages of taking an antidepressant.
    - Suicidal tendencies and worsening behaviour are not part of the synonyms present need therapy to be discontinued. Abrupt changes in behaviour must be communicated by the family of the patient to their respective healthcare provider.
    - The drug has not been approved for use by pediatric patients.
    - It would be best if you did not take silence in case you are allergic to any ingredient contained in the drug or doxepin itself.
    - It should be kept out of the reach of a child.
    - If you end up overdosing on the drug, you should seek medical help or immediately contact a Poison Control Center.


Conclusion
Doxepin is a medication generally used to treat anxiety disorders, depressive disorders, chronic hives, and trouble sleeping. Peak concentrations of doxepin are known to reach an approximate time of two hours. The antidepressant effect of doxepin might take a week or two to develop. On the other hand, the anti-anxiety effects end to be apparent before the occurrence of antidepressant effects.

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